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The role of MAPKs is to facilitate the transmission of signals that regulate various intracellular processes, including immediate hormonal responses, embryonic development, cellular differentiation, proliferation, and programmed cell death (apoptosis)

Its activation involves the hydrolysis of glycerophospholipids on the SN-2 position, producing arachidonic and lysophosphatidic acid, from which molecules and metabolites, such as leukotrienes, prostaglandins, and thromboxane, derive inflammatory response mediators also in cardiovascular diseases ( Another important mechanism by which Hg affects cardiovascular health is through its interaction with essential minerals such as selenium

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Cysteine is instead the precursor of glutathione